Abstract 322: Metformin Inhibits Mitochondrial Permeability Transition Pore Opening in Human Cardiac Mitochondria

Larisa Emelyanova; Sirisha Gudlawar; Milanka Cosic; Mahek Mirza; Frahan Rizvi; Ekhson Holmuhamedov; Francis X. Downey; A. Jamil Tajik; Arshad Jahangir

Abstract 322: Metformin Inhibits Mitochondrial Permeability Transition Pore Opening in Human Cardiac Mitochondria

Larisa Emelyanova, Sirisha Gudlawar, Milanka Cosic, Mahek Mirza, Frahan Rizvi, Ekhson Holmuhamedov, Francis X. Downey, A. Jamil Tajik, Arshad Jahangir

University of Wisconsin - Madison

Research output: Contribution to journal › Meeting abstract

Original language	American English
Journal	Circulation Research
Volume	115
Status	Published - Jul 18 2014

Disciplines

Endocrinology, Diabetes, and Metabolism
Biochemistry
Endocrinology

Cite this

@article{b0440bae7417494a8c43fab5f9c684d0,

title = "Abstract 322: Metformin Inhibits Mitochondrial Permeability Transition Pore Opening in Human Cardiac Mitochondria",

author = "Larisa Emelyanova and Sirisha Gudlawar and Milanka Cosic and Mahek Mirza and Frahan Rizvi and Ekhson Holmuhamedov and Downey, \{Francis X.\} and Tajik, \{A. Jamil\} and Arshad Jahangir",

note = "Background: Type II diabetes mellitus is a major health problem contributing to increased morbidity and mortality with associated cardiovascular diseases. Metformin, an oral antidiabetic agent, has cardioprotective properties independent of their glucose lowering effect; however, mechanisms underlying cardioprotection remain poorly defined.",

year = "2014",

month = jul,

day = "18",

language = "American English",

volume = "115",

journal = "Circulation Research",

}

TY - JOUR

T1 - Abstract 322: Metformin Inhibits Mitochondrial Permeability Transition Pore Opening in Human Cardiac Mitochondria

AU - Emelyanova, Larisa

AU - Gudlawar, Sirisha

AU - Cosic, Milanka

AU - Mirza, Mahek

AU - Rizvi, Frahan

AU - Holmuhamedov, Ekhson

AU - Downey, Francis X.

AU - Tajik, A. Jamil

AU - Jahangir, Arshad

N1 - Background: Type II diabetes mellitus is a major health problem contributing to increased morbidity and mortality with associated cardiovascular diseases. Metformin, an oral antidiabetic agent, has cardioprotective properties independent of their glucose lowering effect; however, mechanisms underlying cardioprotection remain poorly defined.

PY - 2014/7/18

Y1 - 2014/7/18

UR - http://circres.ahajournals.org/content/115/Suppl_1/A322

M3 - Meeting abstract

VL - 115

JO - Circulation Research

JF - Circulation Research

ER -

Abstract 322: Metformin Inhibits Mitochondrial Permeability Transition Pore Opening in Human Cardiac Mitochondria

Disciplines

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Cite this