TY - JOUR
T1 - Atrial fibrillation management: A comprehensive review with a focus on pharmacotherapy, rate, and rhythm control strategies
AU - Lacoste, Jordan L
AU - Szymanski, Thomas W
AU - Avalon, Juan Carlo
AU - Kabulski, Galen
AU - Kohli, Utkarsh
AU - Marrouche, Nassir
AU - Singla, Atul
AU - Balla, Sudarshan
AU - Jahangir, Arshad
N1 - Lacoste JL, Szymanski TW, Avalon JC, et al. Atrial Fibrillation Management: A Comprehensive Review with a Focus on Pharmacotherapy, Rate, and Rhythm Control Strategies. Am J Cardiovasc Drugs. 2022;22(5):475-496. doi:10.1007/s40256-022-00529-6
PY - 2022/9/1
Y1 - 2022/9/1
N2 - Atrial fibrillation (AF) is an increasingly common arrhythmia encountered in clinical practice that leads to a substantial increase in utilization of healthcare services and a decrease in the quality of life of patients. The prevalence of AF will continue to increase as the population ages and develops cardiac comorbidities; thus, prompt and effective treatment is important to help mitigate systemic resource utilization. Treatment of AF involves two tenets: prevention of stroke and systemic embolism and symptom control with either a rate or a rhythm control strategy. Historically, due to the safe nature of medications like beta-blockers and non-dihydropyridine calcium channel blockers, used in rate control, it has been the initial strategy used for symptom control in AF. Newer data suggest that a rhythm control strategy with antiarrhythmic medications with or without catheter ablation may lead to a reduction in major adverse cardiovascular events, particularly in patients newly diagnosed with AF. Modulation of factors that promote AF or its complications is another important aspect of the overall holistic management of AF. This review provides a comprehensive focus on the management of patients with AF and an in-depth review of pharmacotherapy of AF in the rate and rhythm control strategies.
AB - Atrial fibrillation (AF) is an increasingly common arrhythmia encountered in clinical practice that leads to a substantial increase in utilization of healthcare services and a decrease in the quality of life of patients. The prevalence of AF will continue to increase as the population ages and develops cardiac comorbidities; thus, prompt and effective treatment is important to help mitigate systemic resource utilization. Treatment of AF involves two tenets: prevention of stroke and systemic embolism and symptom control with either a rate or a rhythm control strategy. Historically, due to the safe nature of medications like beta-blockers and non-dihydropyridine calcium channel blockers, used in rate control, it has been the initial strategy used for symptom control in AF. Newer data suggest that a rhythm control strategy with antiarrhythmic medications with or without catheter ablation may lead to a reduction in major adverse cardiovascular events, particularly in patients newly diagnosed with AF. Modulation of factors that promote AF or its complications is another important aspect of the overall holistic management of AF. This review provides a comprehensive focus on the management of patients with AF and an in-depth review of pharmacotherapy of AF in the rate and rhythm control strategies.
UR - https://institutionalrepository.aah.org/auroragme/80
UR - https://libkey.io/libraries/1712/pmid/35353353
U2 - 10.1007/s40256-022-00529-6
DO - 10.1007/s40256-022-00529-6
M3 - Article
JO - American journal of cardiovascular drugs : drugs, devices, and other interventions
JF - American journal of cardiovascular drugs : drugs, devices, and other interventions
ER -