TY - JOUR
T1 - Atrioventricular block after congenital heart surgery
T2 - Analysis from the Pediatric Cardiac Critical Care Consortium
AU - Romer, Amy J.
AU - Tabbutt, Sarah
AU - Etheridge, Susan P.
AU - Fischbach, Peter
AU - Ghanayem, Nancy S.
AU - Reddy, Vadiyala Mohan
AU - Sahulee, Raj
AU - Tanel, Ronn E.
AU - Tweddell, James S.
AU - Gaies, Michael
AU - Banerjee, Mousumi
AU - Retzloff, Lauren
AU - Zhang, Wenying
AU - Patel, Akash R.
N1 - Publisher Copyright:
© 2018 The American Association for Thoracic Surgery
PY - 2019/3
Y1 - 2019/3
N2 - Objectives: Our primary aims were to describe the contemporary epidemiology of postoperative high-grade atrioventricular block (AVB), the timing of recovery and permanent pacemaker (PPM) placement, and to determine predictors for development of and recovery from AVB. Methods: Patients who underwent congenital heart surgery from August 2014 to June 2017 were analyzed for AVB using the Pediatric Cardiac Critical Care Consortium registry. Predictors of AVB with or without PPM were identified using multinomial logistic regression. We used these predictors to model the probability of PPM for the subgroup of patients with intraoperative complete AVB. Results: We analyzed 15,901 surgical hospitalizations; 422 (2.7%) were complicated by AVB and 162 (1.0%) patients underwent PPM placement. In patients with transient AVB, 50% resolved by 2 days, and 94% resolved by 10 days. In patients who received a PPM, 50% were placed by 8 days and 62% were placed by 10 days. Independent risk factors associated with PPM compared with resolution of AVB were longer duration of cardiopulmonary bypass (relative risk ratio, 1.04; P =.023) and a high-risk operation (relative risk ratio, 2.59; P <.001). Among patients with complete AVB originating in the operating room, those with the highest predicted probability of PPM had a PPM placed only 77% of the time. Conclusions: In this cohort, postoperative AVB complicated almost 3% of congenital heart surgery cases and 1% of patients underwent PPM placement. Because almost all patients (94%) with transient AVB had resolution by 10 days, our results suggest there is limited benefit to delaying PPM placement beyond that time frame.
AB - Objectives: Our primary aims were to describe the contemporary epidemiology of postoperative high-grade atrioventricular block (AVB), the timing of recovery and permanent pacemaker (PPM) placement, and to determine predictors for development of and recovery from AVB. Methods: Patients who underwent congenital heart surgery from August 2014 to June 2017 were analyzed for AVB using the Pediatric Cardiac Critical Care Consortium registry. Predictors of AVB with or without PPM were identified using multinomial logistic regression. We used these predictors to model the probability of PPM for the subgroup of patients with intraoperative complete AVB. Results: We analyzed 15,901 surgical hospitalizations; 422 (2.7%) were complicated by AVB and 162 (1.0%) patients underwent PPM placement. In patients with transient AVB, 50% resolved by 2 days, and 94% resolved by 10 days. In patients who received a PPM, 50% were placed by 8 days and 62% were placed by 10 days. Independent risk factors associated with PPM compared with resolution of AVB were longer duration of cardiopulmonary bypass (relative risk ratio, 1.04; P =.023) and a high-risk operation (relative risk ratio, 2.59; P <.001). Among patients with complete AVB originating in the operating room, those with the highest predicted probability of PPM had a PPM placed only 77% of the time. Conclusions: In this cohort, postoperative AVB complicated almost 3% of congenital heart surgery cases and 1% of patients underwent PPM placement. Because almost all patients (94%) with transient AVB had resolution by 10 days, our results suggest there is limited benefit to delaying PPM placement beyond that time frame.
KW - congenital heart disease
KW - database
KW - pacemaker
KW - pediatric
UR - https://www.scopus.com/pages/publications/85056883668
UR - https://www.scopus.com/pages/publications/85056883668#tab=citedBy
U2 - 10.1016/j.jtcvs.2018.09.142
DO - 10.1016/j.jtcvs.2018.09.142
M3 - Article
C2 - 30917883
AN - SCOPUS:85056883668
SN - 0022-5223
VL - 157
SP - 1168-1177.e2
JO - Journal of Thoracic and Cardiovascular Surgery
JF - Journal of Thoracic and Cardiovascular Surgery
IS - 3
ER -