TY - JOUR
T1 - D2 Lymphadenectomy for Gastric Cancer
T2 - Advancements and Technical Considerations
AU - Society of Surgical Oncology Gastrointestinal Disease Site Workgroup
AU - Dehal, Ahmed
AU - Woo, Yanghee
AU - Glazer, Evan S.
AU - Davis, Jeremey L.
AU - Strong, Vivian E.
AU - Papenfuss, Wesley A.
AU - Kwon, Steve
AU - Orcutt, Sonia Tewani
AU - Vohra, Nasreen
AU - Eskander, Mariam
AU - Allenson, Kelvin
AU - Nunns, Geoffrey
AU - Ward, Erin
AU - Chai, Chirsty
N1 - Publisher Copyright:
© Society of Surgical Oncology 2024.
PY - 2025/3
Y1 - 2025/3
N2 - Lymphadenectomy (LND) is a crucial component of the curative surgical treatment of gastric cancer (GC). The LND serves to both accurately stage the disease and offer therapeutic benefits. At the time of “curative-intent” gastrectomy, D2 LND is the optimal treatment for patients with locally advanced GC due to its survival benefits and acceptable morbidity. Mastery of the technical aspects of LND, especially D2, requires significant training, adequate case volume, and expertise. This review discusses key aspects of D2 LND, including its status as the standard treatment for locally advanced GC, definition and anatomic borders, technical details, and controversial topics such as splenic hilar dissection and omentectomy. The application of indocyanine green (ICG) fluorescence imaging to elucidate the drainage patterns of GC and to facilitate lymph node (LN) identification is briefly reviewed. Finally, GC standardization and centralization, including surgical treatment, are discussed.
AB - Lymphadenectomy (LND) is a crucial component of the curative surgical treatment of gastric cancer (GC). The LND serves to both accurately stage the disease and offer therapeutic benefits. At the time of “curative-intent” gastrectomy, D2 LND is the optimal treatment for patients with locally advanced GC due to its survival benefits and acceptable morbidity. Mastery of the technical aspects of LND, especially D2, requires significant training, adequate case volume, and expertise. This review discusses key aspects of D2 LND, including its status as the standard treatment for locally advanced GC, definition and anatomic borders, technical details, and controversial topics such as splenic hilar dissection and omentectomy. The application of indocyanine green (ICG) fluorescence imaging to elucidate the drainage patterns of GC and to facilitate lymph node (LN) identification is briefly reviewed. Finally, GC standardization and centralization, including surgical treatment, are discussed.
KW - Gastrectomy/methods
KW - Humans
KW - Indocyanine Green
KW - Lymph Node Excision/methods
KW - Lymph Nodes/surgery
KW - Prognosis
KW - Stomach Neoplasms/surgery
UR - https://www.scopus.com/pages/publications/85210559192
UR - https://www.scopus.com/inward/citedby.url?scp=85210559192&partnerID=8YFLogxK
U2 - 10.1245/s10434-024-16545-6
DO - 10.1245/s10434-024-16545-6
M3 - Review article
C2 - 39589578
AN - SCOPUS:85210559192
SN - 1068-9265
VL - 32
SP - 2129
EP - 2140
JO - Annals of Surgical Oncology
JF - Annals of Surgical Oncology
IS - 3
M1 - 101963
ER -