TY - JOUR
T1 - Factors associated with COVID-19 breakthrough infections in large midwestern healthcare system: Implications for vulnerable healthcare personnel
AU - Rivelli, Anne
AU - Fitzpatrick, Veronica
AU - Copeland, Kenneth
AU - Richards, Jon
AU - Advocate Hematology/Oncology Faculty - Lutheran General, null
N1 - Rivelli A, Fitzpatrick V, Copeland K, Richards J. Factors Associated With COVID-19 Breakthrough Infections in Large Midwestern Healthcare System: Implications for Vulnerable Healthcare Personnel. J Occup Environ Med. 2022;64(8):635-641. doi:10.1097/JOM.0000000000002576
PY - 2022/8/1
Y1 - 2022/8/1
N2 - Objective The aim of the study is to identify factors associated with breakthrough infection among a cohort of Midwestern healthcare personnel (HCP). Methods SARS-CoV-2-positive test results between March 1, 2020, and July 31, 2021, were collected from electronic medical records of HCP to identify breakthrough infections. Results Healthcare personnel who were younger than 35 years, received the Pfizer vaccine, and worked in COVID clinical units had greater adjusted odds of breakthrough infection. COVID infection before full vaccination was associated with reduced odds of breakthrough infection. Conclusions Our study concluded that the most vulnerable HCP are younger, working in COVID-19 clinical units, and received Pfizer-BioNTech primary series vaccines. Healthcare personnel who had COVID before vaccination were at reduced risk of breakthrough infection, indicating that supplemental immunity could better protect at-risk HCP groups.
AB - Objective The aim of the study is to identify factors associated with breakthrough infection among a cohort of Midwestern healthcare personnel (HCP). Methods SARS-CoV-2-positive test results between March 1, 2020, and July 31, 2021, were collected from electronic medical records of HCP to identify breakthrough infections. Results Healthcare personnel who were younger than 35 years, received the Pfizer vaccine, and worked in COVID clinical units had greater adjusted odds of breakthrough infection. COVID infection before full vaccination was associated with reduced odds of breakthrough infection. Conclusions Our study concluded that the most vulnerable HCP are younger, working in COVID-19 clinical units, and received Pfizer-BioNTech primary series vaccines. Healthcare personnel who had COVID before vaccination were at reduced risk of breakthrough infection, indicating that supplemental immunity could better protect at-risk HCP groups.
KW - COVID-19 (epidemiology
KW - prevention & control)
KW - COVID-19 Vaccines
KW - Delivery of Health Care
KW - Health Personnel
KW - Humans
KW - SARS-CoV-2
UR - https://institutionalrepository.aah.org/advocategme/57
UR - https://libkey.io/libraries/1712/10.1097/JOM.0000000000002576
U2 - 10.1097/JOM.0000000000002576
DO - 10.1097/JOM.0000000000002576
M3 - Article
JO - Journal of Occupational and Environmental Medicine
JF - Journal of Occupational and Environmental Medicine
ER -