Right ventricular function in peripartum cardiomyopathy at presentation is associated with subsequent left ventricular recovery and clinical outcomes

Lori A Blauwet; Antonia Delgado-Montero; Keiko Ryo; Josef J Marek; Rami Alharethi; Paul J Mather; Kalgi Modi; Richard Sheppard; Vinay Thohan; Jessica Pisarcik; Dennis M McNamara; John Gorcsan; Aurora Heart Failure / Transplant Faculty

doi:10.1161/CIRCHEARTFAILURE.115.002756

Right ventricular function in peripartum cardiomyopathy at presentation is associated with subsequent left ventricular recovery and clinical outcomes

Lori A Blauwet, Antonia Delgado-Montero, Keiko Ryo, Josef J Marek, Rami Alharethi, Paul J Mather, Kalgi Modi, Richard Sheppard, Vinay Thohan, Jessica Pisarcik, Dennis M McNamara, John Gorcsan, Aurora Heart Failure / Transplant Faculty

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Abstract

BACKGROUND: Peripartum cardiomyopathy has variable disease progression and left ventricular (LV) recovery. We hypothesized that baseline right ventricular (RV) size and function are associated with LV recovery and outcome. METHODS AND RESULTS: Investigations of Pregnancy-Associated Cardiomyopathy was a prospective 30-center study of 100 peripartum cardiomyopathy women with LV ejection fraction (LVEF) CONCLUSIONS: Peripartum cardiomyopathy patients had a high incidence of LV recovery, but a significant minority had persistent LV dysfunction or a major clinical event by 1 year. RV function per echocardiographic fractional area change at presentation was associated with subsequent LV recovery and clinical outcomes and thus is prognostically important.

Original language	American English
Journal	Circulation. Heart failure
DOIs	https://doi.org/10.1161/CIRCHEARTFAILURE.115.002756
Status	Published - May 1 2016

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Blauwet, L. A., Delgado-Montero, A., Ryo, K., Marek, J. J., Alharethi, R., Mather, P. J., Modi, K., Sheppard, R., Thohan, V., Pisarcik, J., McNamara, D. M., Gorcsan, J., & Heart Failure / Transplant Faculty, A. (2016). Right ventricular function in peripartum cardiomyopathy at presentation is associated with subsequent left ventricular recovery and clinical outcomes. Circulation. Heart failure. https://doi.org/10.1161/CIRCHEARTFAILURE.115.002756

Blauwet, LA, Delgado-Montero, A, Ryo, K, Marek, JJ, Alharethi, R, Mather, PJ, Modi, K, Sheppard, R, Thohan, V, Pisarcik, J, McNamara, DM, Gorcsan, J & Heart Failure / Transplant Faculty, A 2016, 'Right ventricular function in peripartum cardiomyopathy at presentation is associated with subsequent left ventricular recovery and clinical outcomes', Circulation. Heart failure. https://doi.org/10.1161/CIRCHEARTFAILURE.115.002756

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title = "Right ventricular function in peripartum cardiomyopathy at presentation is associated with subsequent left ventricular recovery and clinical outcomes",

abstract = "BACKGROUND: Peripartum cardiomyopathy has variable disease progression and left ventricular (LV) recovery. We hypothesized that baseline right ventricular (RV) size and function are associated with LV recovery and outcome. METHODS AND RESULTS: Investigations of Pregnancy-Associated Cardiomyopathy was a prospective 30-center study of 100 peripartum cardiomyopathy women with LV ejection fraction (LVEF) CONCLUSIONS: Peripartum cardiomyopathy patients had a high incidence of LV recovery, but a significant minority had persistent LV dysfunction or a major clinical event by 1 year. RV function per echocardiographic fractional area change at presentation was associated with subsequent LV recovery and clinical outcomes and thus is prognostically important.",

author = "Blauwet, {Lori A} and Antonia Delgado-Montero and Keiko Ryo and Marek, {Josef J} and Rami Alharethi and Mather, {Paul J} and Kalgi Modi and Richard Sheppard and Vinay Thohan and Jessica Pisarcik and McNamara, {Dennis M} and John Gorcsan and {Heart Failure / Transplant Faculty}, Aurora",

note = "Blauwet LA, Delgado-montero A, Ryo K, et al. Right Ventricular Function in Peripartum Cardiomyopathy at Presentation Is Associated With Subsequent Left Ventricular Recovery and Clinical Outcomes. Circ Heart Fail. 2016;9(5) DOI: 10.1161/CIRCHEARTFAILURE.115.002756",

year = "2016",

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day = "1",

doi = "10.1161/CIRCHEARTFAILURE.115.002756",

language = "American English",

journal = "Circulation. Heart failure",

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T1 - Right ventricular function in peripartum cardiomyopathy at presentation is associated with subsequent left ventricular recovery and clinical outcomes

AU - Blauwet, Lori A

AU - Delgado-Montero, Antonia

AU - Ryo, Keiko

AU - Marek, Josef J

AU - Alharethi, Rami

AU - Mather, Paul J

AU - Modi, Kalgi

AU - Sheppard, Richard

AU - Thohan, Vinay

AU - Pisarcik, Jessica

AU - McNamara, Dennis M

AU - Gorcsan, John

AU - Heart Failure / Transplant Faculty, Aurora

N1 - Blauwet LA, Delgado-montero A, Ryo K, et al. Right Ventricular Function in Peripartum Cardiomyopathy at Presentation Is Associated With Subsequent Left Ventricular Recovery and Clinical Outcomes. Circ Heart Fail. 2016;9(5) DOI: 10.1161/CIRCHEARTFAILURE.115.002756

PY - 2016/5/1

Y1 - 2016/5/1

N2 - BACKGROUND: Peripartum cardiomyopathy has variable disease progression and left ventricular (LV) recovery. We hypothesized that baseline right ventricular (RV) size and function are associated with LV recovery and outcome. METHODS AND RESULTS: Investigations of Pregnancy-Associated Cardiomyopathy was a prospective 30-center study of 100 peripartum cardiomyopathy women with LV ejection fraction (LVEF) CONCLUSIONS: Peripartum cardiomyopathy patients had a high incidence of LV recovery, but a significant minority had persistent LV dysfunction or a major clinical event by 1 year. RV function per echocardiographic fractional area change at presentation was associated with subsequent LV recovery and clinical outcomes and thus is prognostically important.

AB - BACKGROUND: Peripartum cardiomyopathy has variable disease progression and left ventricular (LV) recovery. We hypothesized that baseline right ventricular (RV) size and function are associated with LV recovery and outcome. METHODS AND RESULTS: Investigations of Pregnancy-Associated Cardiomyopathy was a prospective 30-center study of 100 peripartum cardiomyopathy women with LV ejection fraction (LVEF) CONCLUSIONS: Peripartum cardiomyopathy patients had a high incidence of LV recovery, but a significant minority had persistent LV dysfunction or a major clinical event by 1 year. RV function per echocardiographic fractional area change at presentation was associated with subsequent LV recovery and clinical outcomes and thus is prognostically important.

UR - https://institutionalrepository.aah.org/hrtfailurefaculty/5

U2 - 10.1161/CIRCHEARTFAILURE.115.002756

DO - 10.1161/CIRCHEARTFAILURE.115.002756

M3 - Article

JO - Circulation. Heart failure

JF - Circulation. Heart failure

ER -

Right ventricular function in peripartum cardiomyopathy at presentation is associated with subsequent left ventricular recovery and clinical outcomes

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